ISBN - 9781464109812
Autor(es) - Harvey Lodish, Chris A. Kaiser, Anthony Bretscher, Angelika Amon, Arnold Berk, Monty Krieger, Hidde Ploegh and Matthew P. Scott
Editora - W.H.Freeman
Ano de Edição - 2012
N º de Páginas - 673
Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. As always, a hallmark of Molecular Cell Biology is the use of experiments to engage students in the history of cell biology and the research that has contributed to the field.
Increased Clarity, Improved Pedagogy:
In the new edition, the authors have scrutinized every chapter with an eye toward bringing out key concepts and making connections easier to follow. Perennially challenging topics, such as cellular energetics, cell signaling and immunology, have been revised to improve student understanding. Coverage of developmental biology has been streamlined to focus on just those key areas central to cell biology courses. Every figure in the book was reconsidered and, if possible, simplified to highlight key lessons. Revised end-of-chapter materials include new questions, including additional Analyze the Data problems to give students added practice at interpreting experimental evidence.
The result is a book that balances currency and experimental focus with attention to clarity, organization, and pedagogy.
Highlights of the New Edition:
- Chapter 1 Molecules, Cells, and Evolution now frames cell biology in the light of evolution: because we all come from the same ancestor cell, the molecules and processes of cell biology are similar in all forms of life. We can use model organisms to study aspects of cell structure and function that have been conserved across millions of years of evolution.
- Chapter 9 Culturing, Visualizing, and Perturbing Cells has been rewritten to include cutting edge methods including FRAP, FRET, siRNA, and chemical biology, making it a state-of-the art methods chapter.
- Cell signaling chapters (Chapters 15 & 16) have been reorganized and illustrated with simplified overview figures, to help students navigate the complexity of signaling pathways.
- Fully Reconceived, Thoroughly Updated Chapter 19 The Eukaryotic Cell Cycle now begins with the concept of "START" (a cell's commitment to entering the cell cycle starting with DNA synthesis) and then progresses through the cycle stages. The chapter focuses on yeast and mammals and uses general names for cell cycle components as much as possible.
Molecules, Cells, and Evolution
Protein Structure and Function
Basic Molecular Genetic Mechanisms
Molecular Genetic Techniques
Genes, Genomics, and Chromosomes
Transcriptional Control of Gene Expression
Post-Transcriptional Gene Control
Culturing, Visualizing, and Perturbing Cells
Transmembrane Transport of Ions and Small Molecules
Moving Proteins into Membranes and Organelles
Vesicular Traffic, Secretion, and Endocytosis
Signal Transduction and G Protein-Coupled Receptors
Signaling Pathways that Control Gene Expression
Cell Organization and Movement I: Microfilaments
Cell Organization and Movement II: Microtubules and Intermediate Filaments
The Eukaryotic Cell Cycle
Integrating Cells into Tissues
Stem Cells, Cell Asymmetry, and Cell Death