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Laboratory Hematology Practice





253.34€ 228.01€
Discount -10 %
ISBN - 9781405162180
Autor(es) - Kandice Kottke-marchant, Bruce Davis (Editores)
Editora - Wiley-Blackwell
Ano de Edição - 2012
N º de Páginas - 776



Description


Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.


Table of Contents

Contributors, viii
Preface, xiii
Abbreviations, xv

I Cellular Analysis, 1
1 Historical Perspective on Cellular Analysis, 3
2 Cellular Morphologic Analysis of Peripheral Blood, 10
3 Automated Cell Analysis: Principles, 26
4 Differential Leukocyte Analysis, 33
5 Automated Platelet Analysis, 48
6 Method Standardization in Cellular Analysis, 59
7 Spurious counts and spurious results on hematology analyzers: platelets, 66
Marc Zandecki, Franck Genevieve, Jérémie Gérard, and Alban Godon
8 Spurious Counts and Spurious Results on Hematology Analyzers: White Blood Cells, Red Blood Cells, Hemoglobin, Red Cell Indices, and Reticulocytes, 79
9 Evaluation of Hematology Analyzers, 96

II Flow Cytometry in Hematologic Diagnosis, 103
10 Flow Cytometric Specimen Collection, Processing, and Reporting, 105
11 Validation and Quality Control in Clinical Flow Cytometry, 115
12 A New Paradigm for Cytometric Analysis, 131

III Molecular Diagnostics, 143
13 Sample Collection, Processing, and Storage for Molecular Genetic Testing, 145
14 Development of Amplification-Based Molecular Genetic Testing in Hematology, 155
15 Single Nucleotide Polymorphisms in Molecular Diagnostics, 168
16 Molecular Cytogenetic (FISH) Analysis of Hematolymphoid Disorders, 181
17 Immunoglobulin and T-Cell Receptor Gene Rearrangement Analysis for Diagnosis of Hematologic Malignancies, 199
18 Minimal Residual Disease Detection in Acute Myeloid Leukemia by RQ-PCR and Multiparameter Flow Cytometry, 220
19 Engraftment Analysis using Short Tandem Repeats following Allogeneic Hematopoietic Cell Transplantation, 234
20 Molecular Profiling Methods in the Diagnosis of Hematologic Disorders, 244
21 The Role of Classical Cytogenetics in Hematologic Diagnosis, 267
IV Bone Marrow Analysis, 279
22 Bone Marrow Processing and Normal Morphology, 281
23 Cytochemical, Immunocytochemical, Histochemical, and Immunohistochemical Staining of Bone Marrow and Peripheral Blood, 300
24 The Myeloproliferative Neoplasms, 315
25 Myelodysplastic Disorders, 331
26 Acute Leukemias, 345
27 Lymphoproliferative Disorders, 364
28 Plasma Cell Disorders, 381
29 Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis, 388
30 Paroxysmal Nocturnal Hemoglobinuria (PNH) Analysis, 399

V Hemostasis and Thrombosis, 407
31 Sample Collection and Processing in Hemostasis, 409
32 Performance and Interpretation of Routine Coagulation Assays, 420
33 Clotting Factors and Inhibitors: Assays and Interpretation, 435
34 Diagnosis of von Willebrand Disease, 447
35 Diagnosis of Fibrinolytic Disorders, 460
36 Laboratory Evaluation of Acquired Coagulation Disorders, 468
37 Platelet Assays and Platelet Dysfunction, 480
38 Thrombophilia: Assays and Interpretation, 492
39 Lupus Anticoagulants, Antiphospholipid Antibodies, and Antiphospholipid Syndrome, 509
40 Heparin-Induced Thrombocytopenia, 526
41 Anticoagulant, Antiplatelet, and Thrombolytic Drugs, 535
42 Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing, 543

VI Special Hematology Techniques, 553
43 Essentials of Immunohematology, 555
44 Analysis of Hemoglobinopathies, Hemoglobin Variants and Thalassemias, 562
45 Nutritional Anemia, 586
46 Hemolytic Anemias Associated with Disorders of Erythrocyte Membrane and Cytoskeleton Proteins, 602
47 Body Fluid Analysis, 615
48 Malaria Analysis, 626
49 Erythrocyte Sedimentation Rate (ESR), 638

VII Point-of-Care Testing, 647
50 Needs Analysis and Selection of Point-of-Care Testing Analyzers, 649
51 Point-of-Care Testing in Hemostasis, 655
52 Point-of-Care Hematology Assays, 668

VIII Management of Information 673
53 Laboratory Management, 675
54 Hematology Quality Practices 686
55 Digital Imaging in Hematology, 707

Index, 719

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