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Asthma and COPD: Basic Mechanisms and Clinical Management

113.37€ 102.03€
Discount -10 %
ISBN - 9780123740014
Autor(es) - Peter J. Barnes, Jeffrey M. Drazen, Stephen I. Rennard, Neil C. Thomson (Editores)
Editora - Academic Press
Ano de Edição -
N º de Páginas -

N º de páginas: 896

2ª Edição

Ano de Edição: 2009


The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.

Key Features
  • Each chapter considers Asthma and COPD in side-by-side contrast and comparison , not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management
  • Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD
  • Most extensive reference to primary literature on both Asthma and COPD in one source.
  • Easy-to-read summaries of the latest advances alongside clear illustrations

    • Contents

      1 Definitions, Epidemiology and Genetics of Asthma and COPD
      2 Epidemiology
      3 Natural History
      4 Genetics of Asthma and COPD
      5 Pulmonary Physiology
      6 Airway Pathology
      7 Airway Remodeling
      8 Animal Models
      9 Mast Cells and Basophils
      10 Dentritic Cells
      11 Macrophages
      12 Eosinophils
      13 Lymphocytes
      14 Neutrophils
      15 Fibroblasts
      16 Epithelial Cells
      17 Mucus and Mucin-Secreting Cells
      18 Airway Smooth Muscle
      19 Tracheobronchial Circulation
      20 Pulmonary Vessels
      21 Adhesion Molecules
      22 Extracellular Matrix
      23 Prostanoids
      24 Leukotrienes and Lipoxins
      25 Reactive Oxygen Species
      26 Chemokines
      27 Cytokines
      28 Matrix Degrading Proteinases
      29 Growth Factors
      30 Nitric Oxide
      31 Transcription Factors
      32 Neural and Humoral Control
      33 Pathophysiology of Asthma
      34 Pathogenesis of COPD
      35 Allergens
      36 Occupational Agents
      37 Infections
      38 Exercise as a Stimulus
      39 Atmospheric Pollutants
      40 Drugs
      41 Diagnosis
      42 Non-invasive Assessment of Airway Inflammation
      43 Imaging
      44 Systemic Manifestations
      45 Cardiovascular Effects
      46 Allergen Avoidance
      47 Smoking Cessation
      48 â2-adrenoceptor Agonists
      49 Anticholinergic Bronchodilators
      50 Theophylline
      51 Corticosteroids
      52 Mediator Antagonists
      53 Antibiotics
      54 Long-term Oxygen Therapy
      55 Immunomodulators
      56 Pulmonary Vasodilators
      57 Ventilator Support
      58 Pulmonary Rehabilitation
      59 Surgery and Other Mechanical Interventions
      60 Other Therapies
      61 Future Therapies
      62 Health Economics
      63 Management of Chronic Asthma in Adults
      64 Asthma Exacerbations
      65 Childhood Asthma
      66 Treatment for Stable COPD
      67 Acute Exacerbations of COPD
68 Education and Self-Management

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